Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data

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Starr: Simple Tiling ARRay analysis for Affymetrix ChIP-chip data

Starr is an extension of the Ringo [6] package for the analysis of ChIP-chip projects. Whereas the latter is specialized to the processing of Nimblegen and Agilent arrays, the former provides all corresponding features for Affymetrix arrays. Data can be read in from Affymetrix CEL-files, or from text files in gff format. Standard quality assessment and data normalization tools are available. St...

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We propose a fast and powerful analysis algorithm, titled Model-based Analysis of Tiling-arrays (MAT), to reliably detect regions enriched by transcription factor chromatin immunoprecipitation (ChIP) on Affymetrix tiling arrays (ChIP-chip). MAT models the baseline probe behavior by considering probe sequence and copy number on each array. It standardizes the probe value through the probe model,...

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ژورنال

عنوان ژورنال: BMC Bioinformatics

سال: 2010

ISSN: 1471-2105

DOI: 10.1186/1471-2105-11-194